Uniaxial Tensile Test and Constitutive Modelling of Human Perivascular Adipose Tissue

All the human blood vessels are surrounded by adipose tissue. Therefore in biomechanics of blood vessels, it is important to deal not only with the constitutive modelling of blood vessels as such but also with the mechanical properties of surrounding tissue. In this study, mechanical response of human perivascular adipose tissue that surrounds the abdominal aorta is concerned. From the performed uniaxial tensile tests, a representative experimental curve was selected to be fitted by hyperelastic models. The experiments showed nonlinear behavior of the tissue with gradual stiffening at higher deformations. Constitutive models Ogden, Gent, Fung were used. The material parameters estimated by nonlinear regression analysis are = 0.001 MPa and = 28, = 0.026 MPa and =0.067, = 0.018 MPa and b = 31.834, respectively. It was concluded that all applied mathematical models predicted material behavior satisfactorily with coefficient of determination 0.995, 0.981, 0.994, respectively.